In conclusion, our results confirmed that rs2071166 in Cx43 may be relevant with an increased atrial septal defect risk. The CC genotype at rs2071166 site in Cx43 was correlated with an increased risk for atrial septal defect (p<0.0001, odds ratio=3.891, 95% confidence interval 1.948–7.772) and the C allele was positively correlated with atrial septal defect (p=0.007, odds ratio=1.567, 95% confidence interval 1.129–2.175). Bioz Stars score: 90/100, based on 2 PubMed citations. The frequency of the single nucleotide polymorphism rs2071166 was significantly higher in atrial septal defect cases than in healthy controls. Mutation Surveyor Demo V4 0 Software, supplied by SoftGenetics, used in various techniques. All data were analysed by using the Statistic Package for Social Science 19.0 software. The promoter region of Cx43 was analysed by sequencing after polymerase chain reaction. A total of 450 paediatric patients were recruited, including 150 cases with atrial septal defect and 300 healthy controls. The aim of our study was to investigate the association of genetic variations of the Cx43 with sporadic atrial septal defect. Its genetic variants can cause several CHD. Mutation Surveyor Demo Bow Wow Ft Omarion Hey Baby Free Mp3 Download Ansi/aami He75 2009 Edition Flippingbook Publisher 2 6 Crack Download. Cx43 is the most prevalent connexin in the mammalian heart during development. The pathogenesis of atrial septal defect still remains unknown. The pins on the map are coloured according to the prevalence of mutations associated with delayed parasite clearance: A site where no isolates with mutations in. Atrial septal defect is one of the most common CHD.
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